Cart
sales@molnova.com
KDM5A covalent inhibitor N73
CAS No. ——
KDM5A covalent inhibitor N73( —— )
Catalog No. M17071 CAS No. ——
KDM5A covalent inhibitor N73 is the the isopropyl ester derivative of N71.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameKDM5A covalent inhibitor N73
-
NoteResearch use only, not for human use.
-
Brief DescriptionKDM5A covalent inhibitor N73 is the the isopropyl ester derivative of N71.
-
DescriptionKDM5A covalent inhibitor N73 is the the isopropyl ester derivative of N71, an irreversible KDM5A inhibitor (IC50=0.22 uM) that covalently interacts with Cys481, >20-fold selectivity over KDM4A.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayChromatin/Epigenetic
-
TargetHistone Demethylase
-
RecptorHistone Demethylase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number——
-
Formula Weight564.745
-
Molecular FormulaC31H40N4O4S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical Nameisopropyl (E)-2-((3-(4-(dimethylamino)but-2-enamido)phenyl)(2-(piperidin-1-yl)ethoxy)methyl)thieno[3,2-b]pyridine-7-carboxylate
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Horton JR, et al. J Med Chem. 2018 Nov 15. doi: 10.1021/acs.jmedchem.8b01219.
molnova catalog
related products
-
KDM5-C70
KDM5-C70 is the cell-permeable derivative of KDM5-C49, potent, selective and cell permeable KDM5 inhibitor with IC50 of 0.3, 0.3 and 0.58 uM for KDM5A, B and C, respectively.
-
BRD9539
BRD9539 is an inhibitor of euchromatin histone methyltransferase 2 (EHMT2) also known as G9a with an IC50 value of 6.3 μM.
-
LSD1 inhibitor 24
LSD1 inhibitor 24 is a novel potent, selective lysine-specific demethylase 1 (LSD1) inhibitor with IC50 of 1 nM.
