KDM5A covalent inhibitor N73
CAS No.
KDM5A covalent inhibitor N73 ( —— )
Catalog No. M17071 CAS No.
KDM5A covalent inhibitor N73 is the the isopropyl ester derivative of N71.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
100MG | Get Quote | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameKDM5A covalent inhibitor N73
-
NoteResearch use only, not for human use.
-
Brief DescriptionKDM5A covalent inhibitor N73 is the the isopropyl ester derivative of N71.
-
DescriptionKDM5A covalent inhibitor N73 is the the isopropyl ester derivative of N71, an irreversible KDM5A inhibitor (IC50=0.22 uM) that covalently interacts with Cys481, >20-fold selectivity over KDM4A.
-
Synonyms——
-
PathwayChromatin/Epigenetic
-
TargetHistone Demethylase
-
RecptorHistone Demethylase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number--
-
Formula Weight564.75
-
Molecular FormulaC31H40N4O4S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical Nameisopropyl (E)-2-((3-(4-(dimethylamino)but-2-enamido)phenyl)(2-(piperidin-1-yl)ethoxy)methyl)thieno[3,2-b]pyridine-7-carboxylate
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Horton JR, et al. J Med Chem. 2018 Nov 15. doi: 10.1021/acs.jmedchem.8b01219.
molnova catalog
related products
-
UNC3866 TFA(1872382-...
UNC3866 TFA is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen.
-
Dot1L-IN-4
Dot1L-IN-4 is a potent disruptor of telomeric silencing 1-like protein (DOT1L) inhibitor.
-
SGC-iMLLT
SGC-iMLLT is a potent and selective MLLT1/3-histone interactions inhibitor(IC50 = 0.26 μM),and is a first-in-class chemical probe displaying cellular target engagement of MLLT1(Kd = 0.129?μM) and MLLT3(Kd = 0.077?μM).